Student Work

Fabrication of a Nutrient Perfusion Enhancing Cartilage Tissue Scaffold

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The main challenge associated with engineering avascular tissue such as cartilage is overcoming the physiological nutrient perfusion limit of 100 µm. Using a 3D printer, a PLA tissue scaffold with a diameter of 6.2 mm was fabricated. The scaffold was threaded with degradable collagen sutures and filled with a chondrogenic cell line suspended in a 4% alginate hydrogel. The scaffold system successfully supported cell proliferation and differentiation for 1 week, indicating efficient nutrient perfusion to the center of the scaffold.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-042915-230907
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  • 2015
Date created
  • 2015-04-29
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Permanent link to this page: https://digital.wpi.edu/show/v692t799q