Currently, there are no clinical methodologies that evaluate the activity of a patient’s milk-producing mammary epithelial cells (MECs) to diagnose insufficient milk supply. Inspired by cancer point-of-care research, this project aimed to design a microfluidic device with single and multi-constriction regions to deform milk-derived MECs and identify cell activity by quantifying their mechanical differences. This device can be used for future projects to carry out fabrication and mechanical testing on resting (non-lactating) and active (lactating) MECs.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Hadad, Brenna
• Low, Stephanie

Subject

• Health
• Innovation
• Project-Based Learning
• Industry

Publisher

• Worcester Polytechnic Institute

Identifier

• 121792
• E-project-042524-153325

Mot-clé

• Maternal Health
• Microfluidics
• Mammary Cells
• Mechanics

Advisor

• Alatalo, Diana
• Billiar, Kristen

Year

• 2024

UN Sustainable Development Goals

• 3 - Good Health and Well-being
• 10 - Reducing Inequality

Date created

• 2024-04-25

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Source

• E-project-042524-153325

Rights statement

• In Copyright

Dernière modification

• 2024-05-21