Modified dextran polymers are used as surfactants in oil in water emulsions, and serve as a hydrophobic boundary layer between the oil droplet surface and its aqueous surroundings, allowing for the formation stable emulsions that consist of biocompatible materials, a possible vector for drug delivery for oil-based drugs. These emulsions consist of Nujol (mineral) oil and a hydrophobically modified destran polymer solution (DexC, DexC, or DexP). Polymer solution concentrations greater than 5 grams per liter allowed for emulsion stability over long periods of time. A combination of centrifugation and lyophilization was determined to be a viable method for storage. Research was performed in collaboration with WPI and ENSIC.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Pistorino, Michael J. 
• Miller, Ian Anthony
• Brancato, Adam Anthony

Publisher

• Worcester Polytechnic Institute

Identifier

• 02D299M

Advisor

• Camesano, Terri Anne

Year

• 2002

Center

• Nancy, France Project Center - MQP

Sponsor

• ENSIC

Date created

• 2002-01-01

Resource type

• Major Qualifying Project

Major

• Chemical Engineering

Rights statement

• In Copyright